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Recent Activity. Recent history Saved searches. Abstract Available from publisher site using DOI. A subscription may be required. Search articles by 'Yuhong Li'. Search articles by 'Rong Wu'. Search articles by 'Yian Tian'. Tian Y 3 ,. Search articles by 'Tianping Bao'. Search articles by 'Zhaofang Tian'. Tian Z 1. Affiliations 3 authors 1. Share this article Share with email Share with twitter Share with linkedin Share with facebook. It has been associated with eosinophil-associated disorders.
We compared serum ECP levels in allergic and non-allergic rhinitis patients and evaluated the association with the eosinophil count and the total IgE level. We retrospectively reviewed medical records and categorized enrolled patients into the allergic AR and non-allergic rhinitis NAR groups. ECP, eosinophil count, and total IgE levels were reviewed in both groups. The association between ECP and the eosinophil count and total IgE level was further evaluated according to commonly detected specific antigens.
Six hundred and ten adults were included in the study. A significant correlation between the ECP level and eosinophil count was demonstrated in AR patients who were skin test positive against house dust mite, animal and pollen allergens. The level of serum ECP was positively correlated with eosinophilia in AR patients regardless of the type of allergen sensitization. However, further study is warranted to verify the role of ECP in the clinical management of allergic rhinitis.